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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 15.76
Human Site: S618 Identified Species: 26.67
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S618 T A P S N S S S L T L S G I K
Chimpanzee Pan troglodytes XP_514658 769 86303 S618 T A P S N P S S L T L S G I K
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S618 T A P S N S S S L T L S G I K
Dog Lupus familis XP_534424 883 97262 S801 N V L S S S S S L M V S G I K
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 G622 S V T P S S C G F T S P G S K
Rat Rattus norvegicus NP_001100006 704 79549 G622 S V P S S S S G F I L P G I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 L660 E N I F T T S L L M I P L L E
Chicken Gallus gallus Q03237 686 77718 S601 T Q P V N F L S R S L N L S S
Frog Xenopus laevis P52551 743 82891 T646 K T E N G T F T N T D L C P Q
Zebra Danio Brachydanio rerio NP_001003867 633 70853 Q564 K E E N V L D Q G F I L G P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 N613 E M S M K A L N E A F N M P S
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 W271 E E A A A N D W W L E N L E K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 D690 D V M L D E G D D C M T S R P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 L255 T T S S I G D L D E F D R R Q
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 93.3 100 60 N.A. 26.6 53.3 N.A. 13.3 33.3 6.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 100 73.3 N.A. 40 66.6 N.A. 40 46.6 33.3 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 6.6 N.A. 0 N.A. 13.3
P-Site Similarity: N.A. 26.6 N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 8 8 8 8 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % C
% Asp: 8 0 0 0 8 0 22 8 15 0 8 8 0 0 0 % D
% Glu: 22 15 15 0 0 8 0 0 8 8 8 0 0 8 8 % E
% Phe: 0 0 0 8 0 8 8 0 15 8 15 0 0 0 0 % F
% Gly: 0 0 0 0 8 8 8 15 8 0 0 0 50 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 15 0 0 36 0 % I
% Lys: 15 0 0 0 8 0 0 0 0 0 0 0 0 0 50 % K
% Leu: 0 0 8 8 0 8 15 15 36 8 36 15 22 8 0 % L
% Met: 0 8 8 8 0 0 0 0 0 15 8 0 8 0 0 % M
% Asn: 8 8 0 15 29 8 0 8 8 0 0 22 0 0 8 % N
% Pro: 0 0 36 8 0 8 0 0 0 0 0 22 0 22 8 % P
% Gln: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 8 15 0 % R
% Ser: 15 0 15 43 22 36 43 36 0 8 8 29 8 15 15 % S
% Thr: 36 15 8 0 8 15 0 8 0 36 0 8 0 0 0 % T
% Val: 0 29 0 8 8 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _